This mosquito suppression strategy is species-specific. Release of male Wolbachia-Aedes aegypti will only impact the Aedes aegypti population in the field, and not other insects.

Irradiation, such as with gamma rays and X-rays, is used to sterilize mass-reared insects so that, while they remain sexually competitive, they cannot produce offspring. SIT does not involve transgenic (genetic engineering) processes.

GM mosquitoes are mosquitoes that have been implanted with a gene that was not originally present or naturally occurring in the insect.